Sodium metavanadate induced cognitive decline, behavioral impairments, oxidative stress and down regulation of myelin basic protein in mice hippocampus: Ameliorative roles of β‐spinasterol, and stigmasterol


Journal article


O. Adebiyi, J. Olopade, F. Olayemi
Brain and Behavior, 2018

Semantic Scholar DOI PubMedCentral PubMed
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APA   Click to copy
Adebiyi, O., Olopade, J., & Olayemi, F. (2018). Sodium metavanadate induced cognitive decline, behavioral impairments, oxidative stress and down regulation of myelin basic protein in mice hippocampus: Ameliorative roles of β‐spinasterol, and stigmasterol. Brain and Behavior.


Chicago/Turabian   Click to copy
Adebiyi, O., J. Olopade, and F. Olayemi. “Sodium Metavanadate Induced Cognitive Decline, Behavioral Impairments, Oxidative Stress and down Regulation of Myelin Basic Protein in Mice Hippocampus: Ameliorative Roles of β‐Spinasterol, and Stigmasterol.” Brain and Behavior (2018).


MLA   Click to copy
Adebiyi, O., et al. “Sodium Metavanadate Induced Cognitive Decline, Behavioral Impairments, Oxidative Stress and down Regulation of Myelin Basic Protein in Mice Hippocampus: Ameliorative Roles of β‐Spinasterol, and Stigmasterol.” Brain and Behavior, 2018.


BibTeX   Click to copy

@article{o2018a,
  title = {Sodium metavanadate induced cognitive decline, behavioral impairments, oxidative stress and down regulation of myelin basic protein in mice hippocampus: Ameliorative roles of β‐spinasterol, and stigmasterol},
  year = {2018},
  journal = {Brain and Behavior},
  author = {Adebiyi, O. and Olopade, J. and Olayemi, F.}
}

Abstract

Exposures to toxic levels of vanadium and soluble vanadium compounds cause behavioral impairments and neurodegeneration via free radical production. Consequently, natural antioxidant sources have been explored for effective and cheap remedy following toxicity. Grewia carpinifolia has been shown to improve behavioral impairments in vanadium‐induced neurotoxicity, however, the active compounds implicated remains unknown. Therefore, this study was conducted to investigate ameliorative effects of bioactive compounds from G. carpinifolia on memory and behavioral impairments in vanadium‐induced neurotoxicity.


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